HIV Prevention Watch: Gilead expanded its lenacapavir licensing for once-yearly HIV PrEP, aiming to speed manufacturing readiness and access across 120 lower-income, high-incidence countries. Cancer Pipeline: Hutchmed said AstraZeneca filed a US NDA for ORPATHYS (savolitinib) plus TAGRISSO (osimertinib) for MET-overexpressing/amplified NSCLC after EGFR-TKI progression, backed by the SAFFRON Phase III trial. Food & Retail Safety: The US recalled 4,596 pounds of ready-to-eat Korean chicken stew distributed across eight states after concerns it was imported without inspection. Energy Costs for Consumers: Trump’s push for a diesel export ban is back in focus as record prices squeeze drivers; the knock-on effects could hit Latin America, where 60%-70% of US diesel exports reportedly go. E-commerce & Value: Shein posted just 1% net revenue growth in H1 2026 as tariff and logistics pressures weighed on margins. Trade & Supply Chains: Mexico’s exports rose 29.3% in Jan–Aug 2026, led by manufactured goods, with AI-linked demand and USMCA talks in the spotlight. Plastic Pollution with a Local Angle: A Vietnam study found plastic waste is cutting small fishers’ income by 10%-25%, while “fishing for litter” programs could turn cleanup into paid work. Cruising Demand: Ambassador Cruise Line plans to rename the Oceania Sirena as Ambella for German-speaking guests, expanding its Europe platform and Caribbean fly-cruise offerings.